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Sr. Associate Engineer, Polysaccharide Process Development - San Carlos California
Company: Vaxcyte Location: San Carlos, California
Posted On: 05/17/2024
Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, periodontitis and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance. WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values: *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. *MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making. Essential Functions: - Assist in designing and executing process development runs focusing on scale down modeling and late-stage process characterization of upstream and primary recovery steps.
- Operate and maintain instrumentation including BSL2 microbial fermenters, TFF systems, depth filtration and centrifugation.
- Record data in electronic laboratory notebooks, and aid in writing technical summary reports.
- Perform analytical assays for process development and in-process manufacturing samples and maintain manufacturing and process development data repositories.
- Perform statistical analysis for manufacturing in-process data for manufacturing process insights and characterization purposes.
- Present data to the team to provide updates on small scale development activities and contribute to technical discussions.
- Perform scaling calculations between large scale manufacturing and small-scale process development operations.
- Review manufacturing documents and transfer in-process data to data repositories. Requirements:
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