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SR. SCIENTIST, ANALYTICAL DEVELOPMENT, RAW MATERIALS - San Carlos California

Company: Vaxcyte Inc.
Location: San Carlos, California
Posted On: 11/16/2024

Join our Mission to Protect Humankind!
Make sure to apply quickly in order to maximise your chances of being considered for an interview Read the complete job description below.
Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, periodontitis and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:

RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.

AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.

LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.

MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary:Vaxcyte is looking for an energetic and talented individual to join our analytical development team. Primary responsibility for the incumbent will include method development, sample testing and data analysis, protocol and report authorization, and analytical method transfer oversight and coordination.Essential Functions:

Independently perform method development for a wide range of analytical techniques used in raw material testing for both quality control and characterization, supporting pre-clinical and clinical projects.
Oversee method transfer to external contract testing labs; Design and perform studies to assist troubleshooting of QC testing, method qualification/validation or issues related to the methods as needed.
Perform analytical testing, data analysis and interpretation and present in various project and functional team meetings.
Collaborate with cross-functional teams to achieve project timelines and goals.
Maintain thorough and accurate records of laboratory work.
Author analytical documents including but not limited to test method, protocols, and reports.Requirements:
- PhD in Analytical Chemistry, Biochemistry or a related field with 5 - 8 years of industry experience; MS with 10 years min industry experience or BS with 13+ years of industry experience in Pharma/Biotech.
- Extensive hands-on experience in a wide range of analytical techniques, such as UV-Vis, HPLC, CE, SDS-PAGE, icIEF, LC-MS, GC-MS, enzyme kinetics, colorimetric and fluorescent plate-based assays, ELISA, Western Blot, etc.
- Expertise in bioassays, particularly enzymatic activity assays, is highly preferred. Knowledge and experience in cell-free protein synthesis are also highly desirable.
- Adeptness in learning: given the broad range of molecular structures and analytical methods involved, the ability to quickly learn and adapt to new techniques and technologies is paramount.
- Ability to analyze complex problems, identify potential solutions, and make informed decisions is critical for the success of this role.
- Familiar with regulatory standards and quality systems (e.g., GLP, GMP).
- Ability to work in a fast-paced team environment, and to consistently meet aggressive timelines while prioritizing tasks for multiple projects.
- Must communicate complex scientific concepts clearly and precisely to a variety of audiences, including junior scientists, cross-functional teams, and non-scientific stakeholders.
- Effective communication and interpersonal skills, with the ability to collaborate cross-functionally and work effectively in a team environment.
- This position is a lab-based role and requires onsite presence.Reports to: Associate Director, Analytical Development, Raw MaterialsLocation: San Carlos, CACompensation:The compensation package will be competitive and includes comprehensive benefits and an equity component.Salary Range: $152,000 - $170,000Vaxcyte, Inc.825 Industrial Road, Suite 300San Carlos, CA 94070We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.
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