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Research Associate 1/2, Analytical Development - Berkeley California

Company: Tbwa Chiat/Day Inc
Location: Berkeley, California
Posted On: 11/17/2024

Research Associate 1/2, Analytical DevelopmentCaribou Biosciences is a leading clinical-stage CRISPR genome-editing biopharmaceutical company dedicated to developing transformative therapies for patients with devastating diseases. Our next-generation genome-editing technology enables superior precision to develop cell therapies that are armored to potentially improve activity against diseases. We believe the future of cell therapy is off-the-shelf, and we are advancing our pipeline of off-the-shelf, or allogeneic, cell therapies from our CAR-T cell therapy platform as readily available treatments for patients with hematologic malignancies and autoimmune diseases.Members of the Caribou herd open their minds to new ideas and welcome diverse perspectives. We proudly assert that teams do their best work when their members are personally engaged, their ideas are taken seriously, and contributions are recognized. Members of the herd work from our headquarters in Berkeley, California, or remotely.We are seeking a Research Associate to join our Analytical Development team. The ideal candidate will collaborate cross-functionally to screen healthy donor blood to manufacture CAR-T cell drug products, provide testing support to in-house studies, method development, and technical transfers to external organizations. This role will report to the Senior Scientist and will be primarily on-site at our facility in Berkeley, CA.Principal Duties and Responsibilities:

  • Prepare samples and perform assays to screen healthy donor blood by ddPCR for use in downstream manufacturing
  • Execute in-house testing and analyze data
  • Support the development of sensitive and robust analytical test methods to screen healthy donor cells, release drug products and critical materials, characterize drug products, study stability, and optimize manufacturing processes
  • Support method transfer, training, and qualification activities at external testing facilities
  • Write test method procedures, protocols, and development reportsMinimum Qualifications:
    • BS degree in biochemistry or molecular cell biology
    • Minimum 2+ years of laboratory experience
    • Experience performing analytical methods such as ddPCR, qPCR, cell culture, and ELISA
    • Experience in cell-based bioassay, flow cytometry, and Luminex is a plus
    • Ability to work independently on projects and take initiatives
    • Good writing/presentation skills and electronic notebook skillsCaribou compensation and benefits include:
      • Comprehensive compensation package, which includes competitive salary, bonus, and equity for all employees
      • Salary Range: $80,000 to $95,000. This represents the present low and high end of the Company's pay range for this position. Actual pay will vary based on various factors, including but not limited to location, skill, experience, and performance.
      • Generous paid vacation time, in addition to company-observed holidays and floating holidays
      • Excellent medical, dental, and vision insurance
      • 401(k) retirement savings plan, which includes matching employer contributions
      • Employee stock purchase plan (ESPP)The benefits and stock purchase described above are subject to the terms and conditions of any governing plans, policies, practices, agreements, or other materials or documents as in effect from time to time, including but not limited to terms and conditions regarding eligibility.Caribou is an equal opportunity employer and does not discriminate based on race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law. In addition, Caribou prohibits the harassment of any individual on any of the bases listed above or any other characteristics protected under federal, state, or local laws.Legal authorization to work in the United States is required. In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire.
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