Computational Biology Research Scientist - Santa Clara California

Company: F. Hoffmann-La Roche Gruppe
Location: Santa Clara, California
Posted On: 02/03/2025

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people's varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.The PositionA healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche.Roche Diagnostics is seeking a talented and motivated research scientist to join our computational biology research and early development team to contribute to early research and development of state-of-the-art next generation sequencing based liquid biopsy diagnostic assays. The ideal candidate should have a strong background in bioinformatics, computational biology, or a related field, and will be instrumental in analyzing genomic data and developing algorithms to support the innovation and development of novel next generation sequencing workflows and their application in the translational setting towards innovative sequencing based liquid biopsy diagnostic solutions.The Opportunity:

• Be part of a growing, talented and dynamic team.
• Contribute to large interdisciplinary cross-organizational collaborations with global impact.
• Develop and apply computational tools for the analysis of high-throughput genomic, transcriptomic, and epigenetic data.
• Collaborate with experimental and computational researchers to design, analyze, and interpret molecular experiments.
• Work with next-generation sequencing (NGS) data including but not limited to RNA-Seq, ChIP-Seq, Methyl-Seq, Hybrid Capture and Whole Genome Sequencing.
• Use existing analytical tools and packages together with custom scripting and algorithm development to uncover insights from complex datasets.
• Prepare detailed reports and presentations of findings for stakeholders and team meetings.
• Support the maintenance and operation of bioinformatics infrastructure.
• Career development and upskilling.Who you are:
  • You hold a Master's degree with 4 years of relevant experience or a PhD with 2 years of experience in Bioinformatics, Computational Biology, Statistics, Genetics, or a related field.
  • You have proven analytical experience working with raw NGS data types (FASTQ and BAM) from genomic, Methyl-seq or ChIP-seq experiments.
  • You are proficient in Python and Bash programming.
  • You have experience with bioinformatics programming tools and databases (e.g., Conda, Git, Bioconductor, Biopython, BLAST, BWA, SAMtools, BedTools, DeepTools, GATK, UCSC Genome Browser etc).Preferred Qualifications:
    • You have a thorough understanding of molecular biology, genomic technologies, and their applications.
    • You have experience and in-depth knowledge of cancer biology.
    • You have proven analytical experience in ChIP-seq.
    • You have experience with machine learning and statistical data analysis.
    • You have demonstrated the ability to handle large datasets and computational workflows in high performance computing environments.
    • You have strong problem-solving skills and a collaborative mindset.
    • You have excellent written and verbal communication skills.The expected salary range for this position based on the primary location of Santa Clara, CA is 116,800--216,800. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.This position also qualifies for the benefits detailed at the link provided below.Relocation benefits are not provided.Who we areAt Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form .
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