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Research Professional 1-Preclinical Research (Department of Neuroscience) - Minneapolis Minnesota
Company: University of Minnesota Location: Minneapolis, Minnesota
Posted On: 01/25/2025
Apply for JobJob ID366367 LocationTwin Cities Job FamilyResearch Full/Part TimeFull-Time Regular/TemporaryRegular Job Code8351PR Employee ClassCivil Service Add to Favorite JobsEmail this Job About the Job The in the Department of Neuroscience is seeking a Research Professional to join its team.Total effort for the section below (60%) - Colony management of genetically modified mice (including models of Alzheimer's disease and related dementias). - Performance of various husbandry techniques including breeding procedures, microchip implantation, animal identification, tissue collection (tail snips, brain microdissection and harvesting), cardiac perfusions, and database management. - Coordinate with project managers (graduate students, undergraduate students and researchers) in developing and maintaining breeding plans for various experimental studies. - Cognitive/behavioral testing of mice using the Barnes maze, Y maze or Restaurant Row maze. This also includes data analysis using AnyMaze and exported data files for secondary analyses in Excel, JMP for statistics and/or MatLab. Total effort for the section below (10%) - Performance of laboratory techniques involved in genotyping genetically modified mice (i.e. DNA extraction, and PCR) - Performance of brain tissue sectioning using a vibratome. - Assist with general lab maintenance as needed including preparation of solutions, preparing glassware, and autoclaving lab supplies. Total effort for the section below (30%) - Performance of biochemical assays (SDS-PAGE, CN-PAGE, western blotting, dot blotting) and cell culture techniques. - Performance of immunohistological assays (immunofluorescent labeling of brain tissue sections) and confocal imaging techniques. This also includes data analysis using the Imaris software package. Qualifications All required qualifications must be included in the application materialsRequired Qualifications: - B.A./B.Sc. in Biological or Behavioral Sciences or a combination of related education and work experience to equal four years.
- Must be able to work with genetically modified mice including identification procedures, sacrificing animals, and general husbandry.
- Experience with molecular biological techniques (e.g., DNA extraction and qPCR) and biochemical assays (e.g. Western blot, immunohistochemistry, and immunoprecipitation).
- Knowledge of Microsoft Office, Google Suite and database management systems (Access or other).
- Self-motivated, ability to work independently and as a team by coordinating schedule and work assignments with other laboratory personnel. This position requires excellent attention to detail and communication skills.Preferred Qualifications:
- Completed coursework in Neuroscience or Neurobiology.
- Experience with murine husbandry practices and/or mouse behavioral testing.
- Experience in research lab setting.
About the Department The major research goal of our laboratory is to understand the molecular and cellular mechanisms triggered by proteins abnormally aggregating in cerebral brain tissues during the course of neurodegenerative disorders, with a specific focus on Alzheimer's disease. Empowered by this new knowledge, we aim at developing therapeutic strategies to counter the action of these molecules in preclinical models of the disease. To learn more visit Pay and Benefits Pay Range: $20-$22/hour; depending on education/qualifications/experienceTime Appointment: 75%-100% Appointment Position Type: Civil-Service & Non-Faculty Labor Represented StaffPlease visit the Office of Human Resources website for more information regarding benefit eligibility.The University offers a comprehensive benefits package that includes: |
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